Skin Cancer Charts Graphs

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From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Sun, May 11, 2008 at 6:20 PM
Subject: Breast cancer expression of E-cadherin does not differ between patients with positive and negative oncological history.
To: mesothelioma77@gmail.com

[1]Adv Med Sci. 2008 Apr 18; 1-5
Brużewicz S, Matkowski R, Swiątoniowski G, Suder E, Setta M, Połozowski A, Zychowicz K, Szynglarewicz B, Kornafel J

Purpose: The question of whether or not non-sporadic breast malignancies have different immunohistochemical features than sporadic malignancies has not been investigated previously. Consequently, the purpose of this study was to compare the expression of E-cadherin (EC) in breast cancer patients with positive and negative oncologic histories.Material and Methods: The study included 98 breast cancer patients divided into two groups: 1) without the personal or familial history of previous malignancies, and 2) with the personal history of previous malignancies and/or with the data on cancer episodes in first- and/or second-degree relatives.Results: There were no significant differences in the expression of EC between breast malignancies of the two groups. Moreover, statistical relationships were not observed between the positive or negative oncologic history, the age, and the menopausal status of patients, or histological tumor grade.Conclusions: Although the results of our series revealed no significant differences in the expression of EC between assumed sporadic and assumed non-sporadic malignancies, there is a need for further comparative studies on the immunohistochemistry of both the breast carcinoma types in order to find the other biological markers that could suggest or exclude cancer susceptibility in a given patient. Nevertheless, the results of our study suggest that EC immunohistochemistry cannot be used as a surrogate marker for screening for hereditary breast cancer.

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Source: http://www.hubmed.org/display.cgi?uids=18467270
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---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Sun, May 11, 2008 at 6:20 PM
Subject: Surgeon-performed ultrasound reliably predicts skin spacing and may decrease the rate of MammoSite balloon catheter explantation in patients undergoing brachytherapy for breast cancer.
To: mesothelioma77@gmail.com

[1]Am J Surg. 2008 May 6;
Wilkinson JB, Boyle T, Song J, Kilbride K, Miltenburg D

OBJECTIVE: The purpose of this study was to determine if the distance from the skin to the seroma cavity, as measured with ultrasound (US) before catheter placement, correlated with the distance from skin to MammoSite balloon catheter as measured on computerized axial tomography (CAT) after catheter placement. METHODS: US was used to measure the distance from the skin to the seroma cavity, and then the MammoSite balloon catheter was inserted. Skin-to-balloon distance was then measured using CAT. Statistical analysis was performed to determine correlation between the 2 measurements. RESULTS: Our cohort consisted of 70 patients. US distance correlated with CAT distance (Pearson correlation coefficient .70). Mean US distance was 10.8 mm (SD 4.5 mm); mean CAT distance was 11.9 mm (SD 7.5 mm); and mean difference between the 2 measurements was -1.1 mm (SD 6.1 mm). A US measurement >/=7.6 mm predicted successful completion of MammoSite brachytherapy in 98% of patients. Patients with skin-to-seroma cavity distance /=7.6 mm skin-to-seroma cavity distance on US had a higher completion rate of MammoSite brachytherapy treatment.

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Source: http://www.hubmed.org/display.cgi?uids=18466860
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