Fwd: LegalView Mesothelioma Blog Reports That Asbestos Exposure Slows ...

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From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: LegalView Mesothelioma Blog Reports That Asbestos Exposure Slows ...
To: mesothelioma77@gmail.com


PR.com - ... mineral was used because of its resistance to heat and fire damage as well as its strength, however, it was discovered that the inhalation of asbestos fibers and dust was highly toxic to individuals and can cause asbestosis and mesothelioma cancer ...

Wed, 20 Feb 2008 07:48:00 GMT

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Source: http://www.pr.com/press-release/72902
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Fwd: [A Patient with Gastric Cancer Complicated with Multiple Spinal Bone Metastases Showing a Complete Remission to Combination of S-1 and CDDP.]

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: [A Patient with Gastric Cancer Complicated with Multiple Spinal Bone Metastases Showing a Complete Remission to Combination of S-1 and CDDP.]
To: mesothelioma77@gmail.com


[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 311-313
Kawano I, Yufu M

The patient was a 66-year-old man. Total gastrectomy was performed due to BorrmannVtype moderately differentiated adenocarcinoma of the middle part of the stomach. The final diagnosis was UM 7x6 cm, sT3, sN1, sH0, sP0, sM0, sCY0, sStage IIIA, PM (-), DM (-), D2+alpha, Cur B, ly2, v2. Because CEA had increased slowly from ten months after the operation, it was judged a possibly partial relapse. Twice-administered CDDP 80 mg/body and S-1 80 mg on the eighth day served to decrease CEA. He was hospitalized again due to fracture of the spine, though he left the hospital once. The patient was diagnosed by MRI inspection of the vertebrae thoracicae and the lumbar vertebra as multiple spinal bone metastases. After CDDP 60 mg/body of day 8 was administered twice at S-1 80 mg/day, CEA became normal. Osteolytic changes of the spinal bone disappeared. The 24 months from February 2004 to January 2006 passed without additional treatment. His CEA value tended to rise within the normal range in February 2006. After that, the CEA level increased with a 4-week cycle of 2 weeks of S-1 40-80 mg alternating with a two-week rest.



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Source: http://www.hubmed.org/display.cgi?uids=18281772
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Fwd: [Two Advanced/Recurrent Breast Cancer Cases Effectively Treated by Trastuzumab/Capecitabine Combination Therapy.]

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: [Two Advanced/Recurrent Breast Cancer Cases Effectively Treated by Trastuzumab/Capecitabine Combination Therapy.]
To: mesothelioma77@gmail.com


[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 319-322
Inoue S, Inoue M, Takahashi H, Inoue A, Kunitomo K, Fujii H

Trastuzumab/capecitabine combination therapy was performed for two advanced/recurrent breast cancer cases with acute deterioration of the disease. The time until partial response in the first case was 7 months and in the second case 12 months. Adverse events were slight, though a standard dose as a single drug was used for each drug. The treatment time course was shortened because capecitabine was an oral drug. Therefore, this combination therapy was expected to maintain high quality of life and obtain a high response rate.



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Source: http://www.hubmed.org/display.cgi?uids=18281774
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Fwd: [A 23-Year Delayed Locoregional Recurrence of Breast Carcinoma Following Mastectomy.]

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: [A 23-Year Delayed Locoregional Recurrence of Breast Carcinoma Following Mastectomy.]
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[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 323-326
Ogo E, Etou H, Suzuki G, Suefuji H, Tsuji C, Hattori C, Hayabuchi N

A 77-year-old woman who underwent a right modified radical mastectomy 23 years ago with no further adjuvant treatment presented with a right chest wall mass (3x4x2 cm) at the scar. She had no symptoms nor metastasis. The laboratory data were normal including tumor marker. The mass was diagnosed as compatible with a local recurrence tumor from the previous breast cancer on the ultrasonography and chest CT. After obtaining her informed consent for the therapy, we performed 60 Gy/30 fr radiotherapy on the recurrent tumor on her right chest wall with concurrent oral chemo-endocrine therapy. The first regimens were tamoxifen 20 mg/day and 5'-DFUR 600 mg/day, followed by tore- mifene 80 mg/day and 5'-DFUR 600 mg/day, and then the tumor disappeared. But three years later, we found tumor regrowth. We changed the regimen, giving 5'-DFUR 1,200 mg/day and cyclophosphamide 100 mg/day for 2 weeks followed by a 1-week drug-free period, then added 10 Gy/5 fr radiotherapy and hyperthermia twice a week. Final regimens were anastrozole 1 mg/day and capecitabine 900 mg/day. The recurrent tumor decreased and the disease stabilized. After these therapies, she had very good quality of life. We recommend radiation and/or hyperthermia with concurrent oral chemo-endocrine therapy as useful for the delayed recurrence of elderly breast cancer after a modified radical mastectomy.



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Source: http://www.hubmed.org/display.cgi?uids=18281775
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Fwd: The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes.

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes.
To: mesothelioma77@gmail.com


[1]Genet Med. 2008 Feb; 10(2): 121-130
O'Neill SC, White DB, Sanderson SC, Lipkus IM, Bepler G, Bastian LA, McBride CM

PURPOSE:: To examine the feasibility of offering genetic susceptibility testing for lung cancer (GSTM1) via the Internet to smokers who were blood relatives of patients with lung cancer. Outcomes include proportion who logged on to the study website to consider testing, made informed decisions to log on and to be tested. METHODS:: Baseline measures were assessed via telephone survey. Participants could choose to log on to the study website; those who did were offered testing. Informed decisions to log on and to be tested were indicated by concordance between the decision outcome and test-related attitudes and knowledge. RESULTS:: Three hundred four relatives completed baseline interviews. One hundred sixteen eligible relatives expressed further interest in receiving information via the web. Fifty-eight logged on and 44 tested. Those logging on expressed greater quit motivation, awareness of cancer genetic testing, and were more likely to be daily Internet users than those who did not log on. Approximately half of the sample made informed decisions to log on and to be tested. CONCLUSION:: Interest in a web-based protocol for genetic susceptibility testing was high. Internet-delivered decision support was as likely as other modalities to yield informed decisions. Some subgroups may need additional support to improve their decision outcomes.



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Source: http://www.hubmed.org/display.cgi?uids=18281920
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Fwd: Musculoskeletal syndromes associated with malignancy (excluding hypertrophic osteoarthropathy).

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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: Musculoskeletal syndromes associated with malignancy (excluding hypertrophic osteoarthropathy).
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[1]Curr Opin Rheumatol. 2008 Jan; 20(1): 100-5
Naschitz JE, Rosner I

PURPOSE OF REVIEW: To examine recent data about the association between rheumatic disorders and cancer. This article focuses on paraneoplastic rheumatic disorders, which usually precede by a short period of time the diagnosis of malignancy, and on malignant transformation, which occurs late in the course of rheumatic disorders. Evidence of causality between malignancies and rheumatic disorders was reviewed based on statistical indicators (standardized incidence ratios and odds ratios) and by applying Bradford Hill's criteria of causality. RECENT FINDINGS: Firm epidemiological evidence was found attesting that dermatomyositis and polymyostis may present as paraneoplastic syndromes. Several other musculoskeletal disorders may be present akin to paraneoplastic syndrome, based on clinicians' impressions, but with scarce epidemiological evidence supporting a causal determinism. In contrast, robust evidence has accumulated on the role of longstanding rheumatoid arthritis, Sjögren's syndrome and systemic sclerosis as premalignant conditions. Evidence that systemic lupus erythematosus may evolve into lymphoma is equivocal. SUMMARY: The link between malignancies and rheumatic disorders may impact on clinical practice. First, paraneoplastic rheumatic syndromes can provide the clinician with hints for earlier diagnosis of occult cancer. Second, the risk of malignant transformation during the course of rheumatic disorders may motivate the search for strategies aimed at prevention.



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Source: http://www.hubmed.org/display.cgi?uids=18281865
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Fwd: Researchers develop cancer breath test

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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: Researchers develop cancer breath test
To: mesothelioma77@gmail.com

The test may help doctors detect cancer cells . A new laser analyser might be able to help doctors detect cancer, asthma or other diseases by sampling a patient's breath.

Wed, 20 Feb 2008 04:10:20 GMT

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Source: http://www.abc.net.au/news/stories/2008/02/20/2167835.htm
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Fwd: Opportunities in China Lure Scientists Home

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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: Opportunities in China Lure Scientists Home
To: mesothelioma77@gmail.com

By Ariana Eunjung Cha Washington Post Foreign Service Wednesday, February 20, 2008; Page D01 SHANGHAI -- Sheng Huizhen's life story is typical of immigrants who succeeded in America.

Wed, 20 Feb 2008 04:42:33 GMT

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Source: http://www.washingtonpost.com/wp-dyn/content/article/2008/02/19/AR2008021902509.html?nav=rss_world
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