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Friday, March 28, 2008

Fwd: Health Officials to Discuss Asbestos-Like Mineral in Dunn County



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Fri, Mar 28, 2008 at 3:15 PM
Subject: Health Officials to Discuss Asbestos-Like Mineral in Dunn County
To: mesothelioma77@gmail.com


Health officials have been sampling an asbestos-like mineral found on Dunn County roads, and they say its particles are the right size to collect in the lungs of people who breathe it.

Fri, 28 Mar 2008 16:56:01 GMT


Source: http://www.kmot.com/News_Stories.asp?news=17046
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Mesothelioma Cancer  Explained

 

In this disease, malignant cells develop in the mesothelium, a protective lining that covers perfectly of the length's internal organs. Unlike lung cancer, there is no association between mesothelioma and smoking Mesothelioma is the word used to describe a cancerous tumor that involves the mesothelial cells of an organ, often the lungs, heart, or abdominal organs. Malignancies involving mesothelial cells in these length cavities are known as malignant mesothelioma, which may be localized or diffuse.

 

Mesothelioma is a system of cancer that is almost always caused by previous exposure to asbestos Malignant mesothelioma is a rare type of cancer in which malignant cells are found in the sac lining the chest or abdomen.

 

 A history of exposure to asbestos may increase clinical suspicion for mesothelioma. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma.

  A physical examination is performed, followed by chest X-ray and often lung function tests. Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and suffering due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever.

 

Diagnosing mesothelioma is often difficult, because the symptoms are similar to those of a number of other conditions. Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. The X-ray may reveal pleural thickening commonly seen after asbestos exposure and increases suspicion of mesothelioma.

 

Tissue is removed, placed under the microscope, and a pathologist makes a definitive diagnosis, and issues a pathology report. Malignant mesothelioma is often just called simply Mesothelioma and is a aptitude of lung cancer that is quite rare. Malignant mesothelioma is more humble in men, with a male-to-female ratio of 3:1. 

 

It can also occur in children; however, these cases are not thought to be associated with asbestos exposure.

 Malignant mesothelioma has also been linked to medicinal radiation using thorium dioxide and zeolite, a silicate in the soil.

 Malignant mesothelioma has a peak incidence 35-45 years after asbestos exposure. Surpassingly people with malignant mesothelioma have worked on jobs where they breathed asbestos. Transcendently malignant mesotheliomas let complex karyotypes, with extensive aneuploidy and rearrangement of much chromosomes.

 

Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.

 Mesothelial cells normally line the measurement cavities, including the pleura, peritoneum, pericardium, and testis.

 

Treatment options for the management of malignant mesothelioma include surgery, chemotherapy, radiation, and multimodality treatment. Surgery in patients with disease confined to the pleural space is reasonable.

 Extrapleural pneumonectomy is a more extensive procedure and has a higher mortality rate. Recently, the mortality rate has been lowered to 3.8%. It involves dissection of the parietal pleura; division of the pulmonary vessels; and en bloc resection of the lung, pleura, pericardium, and diaphragm followed by reconstruction. It provides the downright local control because it removes the global pleural sac along with the lung parenchyma.

 Pleurectomy with decortication is a more limited procedure and requires less cardiorespiratory reserve. It involves dissection of the parietal pleura, incision of the parietal pleura, and decortication of the visceral pleura followed by reconstruction. It has a morbidity rate of 25% and a mortality rate of 2%. It is a difficult procedure because the tumor encases the whole pleura; the local recurrence rate is high.

 

 

There are now a number of cancer treatment options handy to mesothelioma victims. Extrapleural pneumonectomy for selected patients with very early stage disease may gain ground recurrence-free survival, but the impact it has on overall survival is unknownat this time. The demand for of radiation corrective in pleural mesothelioma has been shown to temper aches and in the majority of patients that are treated. But unfortunately, the duration of symptom control is short-lived.

Ling ling
 

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Fwd: Testicular cancer and hormonally active agents.



---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Fri, Mar 28, 2008 at 3:15 PM
Subject: Testicular cancer and hormonally active agents.
To: mesothelioma77@gmail.com


[1]J Toxicol Environ Health B Crit Rev. 2008 Mar; 11(3-4): 260-75
Garner M, Turner MC, Ghadirian P, Krewski D, Wade M

Testicular cancer (TC) is a rare form of cancer, accounting for 1% of all new cancer cases in Canadian males. TC is the most common malignancy among young men, aged 25-34 yr old. Over previous decades, the incidence of TC has increased in many Western countries. Countries with a sufficiently long period of cancer registration, such as Denmark, document this trend back to the first half of the 20th century. The etiology of TC remains poorly understood. Most of the established risk factors are likely related to in utero events, including some factors that are purported to be surrogate measures for exposure to endogenous estrogens. The correlation of TC with other testicular abnormalities and with pregnancy factors led to the proposal that these conditions are a constellation of sequelae of impairment of testicular development called testis dysgenesis syndrome. There is some limited evidence suggesting that exposure to pharmacological estrogens may contribute to some cases of TC. There is currently no compelling evidence that exposure to environmental estrogenic or other hormonally active substances is contributing to the rise in TC incidence observed in Western nations over the last several decades; however, this question has not been extensively studied. The (1) rarity of this condition in the population, (2) long lag time between the presumed sensitive period during fetal development and clinical appearance of the condition, and (3) lack of a good animal model to study the progression of the disease have greatly hindered the understanding of environmental influences on TC risk.



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Source: http://www.hubmed.org/display.cgi?uids=18368556
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Fwd: A Novel Serine Phosphorylation Site Detected in the N-Terminal Domain of Estrogen Receptor Isolated from Human Breast Cancer Cells.



---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Fri, Mar 28, 2008 at 3:15 PM
Subject: A Novel Serine Phosphorylation Site Detected in the N-Terminal Domain of Estrogen Receptor Isolated from Human Breast Cancer Cells.
To: mesothelioma77@gmail.com


[1]J Am Soc Mass Spectrom. 2008 Mar 4;
Britton DJ, Scott GK, Schilling B, Atsriku C, Held JM, Gibson BW, Benz CC, Baldwin MA

Activated estrogen receptor (ERalpha) plays a critical role in breast cancer development and is a major target for drug treatment. Serine phosphorylation within the N-terminal domain (NTD) contributes to ERalpha activation and may also cause drug resistance. Previous biochemical identification of phosphorylated ERalpha residues was limited to protein artificially overexpressed in transfected cell lines. We report mass spectrometric methods that have allowed the identification of a new site within the NTD of ERalpha isolated from cultured human breast cancer cells. Immunoprecipitation, trypsin digestion, and analysis by nano-LC-ESI-MS/MS (Q-STAR, MDS Sciex) and vMALDI-MS(n) (Finnigantrade mark LTQtrade mark, Thermo-Electron) identified peptides containing 8 of 14 serine residues within the NTD, one being partially phosphorylated Ser-167, known but not previously reported by MS. Chymotrypsin digestion revealed other known sites at Ser-102/104/106 and 118. Tandem methods developed for the peptide containing Ser-118 and the use of hypothesis-driven experiments-i.e., the assumption that an intact phosphopeptide showing no molecular ion might yield fragment ions including loss of phosphoric acid in vMALDI-MS/MS-allowed the identification of a novel site at Ser-154. Quantitation by selected reaction monitoring demonstrated 6-fold and 2.5-fold increases in Ser-154 phosphorylation in estradiol- and EGF-treated cells, respectively, compared to controls, confirmed by immunoblotting with a novel rabbit polyclonal antibody. Thus, the protein isolation and MS strategies described here can facilitate discovery of novel phosphorylation sites within low abundance, clinically important cancer targets like ERalpha, and may thereby contribute to our understanding of the role of phosphorylation in the development of breast cancer.



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Source: http://www.hubmed.org/display.cgi?uids=18367407
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Fwd: Health Highlights: March 28, 2008



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Fri, Mar 28, 2008 at 3:15 PM
Subject: Health Highlights: March 28, 2008
To: mesothelioma77@gmail.com


CF Drug Shows Promise An investigational oral drug called VX-770 showed promising results in treating cystic fibrosis patients who carry the G551D mutation of CF, the Cystic Fibrosis Foundation said.

Fri, 28 Mar 2008 17:38:47 GMT


Source: http://www.healthday.com/Article.asp?AID=614002
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Low Car Insurance Rate Canada

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Pet Dogs

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Transport Dog Crates

Dog Transport

Air Filled Dog Bed: Your Best Friends Comfort

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Related Articles

 

Health Wellness Sites;

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Relieve Stress Anxiety Tensions

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http://www.lingwellness.com/privatestudentloans.php

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 http://www.lingwellness.com/transportdogcrates.php

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Fwd: Hidden tobacco cash behind cancer study spawns worry



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Mar 27, 2008 at 3:49 PM
Subject: Hidden tobacco cash behind cancer study spawns worry
To: mesothelioma77@gmail.com


By MARILYNN MARCHIONE and STEPHANIE NANO, Associated Press Writers The disclosure of hidden tobacco money behind a big study suggesting that lung scans might help save smokers from cancer has shocked the ...

Thu, 27 Mar 2008 19:22:54 GMT


Source: http://www.kidk.com/news/health/17053076.html
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School Consolidation Loan

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Consolidate Debt Loans: For Better Debt Management

Mortgage Loans. Mortgage Loan Refinancing In Britain

Mortgage Refinancing: The Info You Need Before You Refinance

What is Subprime Mortgage?

Mortgage Loan Refinancing In Britain

Mortgage Foreclosure Appraisal

Real Estate: Important Things to Remember

MS Beach Vacation Condos

Foreclosures Bank Owned

Real Estate Marbella

Franklin TN Real Estate

Hud Homes Savannah Georgia

Margate Real Estate

Hud Approved Builders

Regulations Preventing Foreclosure

Insurance Premiums and Your DUI, DWI

The Role of Insurance Insurance Defined

Low Car Insurance Rate Canada

 97402 Dui Classses

Austin DWI Attorney Info

Florida DWI Arrest

Austin DWI and DUI Defined

Florida Dwi Defense

http://www.lingwellness.com/privatestudentloans.php

http://www.lingwellness.com/mortgagerefinancing.php

http://www.lingwellness.com/privatestudentloans.ph

http://www.lingwellness.com/transportdogcrates.php

http://www.lingwellness.com/airfilleddogbed.php

http://www.lingwellness.com/dogtransport.php

http://www.lingwellness.com/uniquedogcollars.php

http://www.lingwellness.com/airfilleddogbedyourbestfriendscomfort.php

http://www.lingwellness.com/petdogs.php

Pet Dogs

Air Filled Dog Bed

Transport Dog Crates

Dog Transport

Air Filled Dog Bed: Your Best Friends Comfort

Unique Dog Collars

 

Related Articles

 

Health Wellness Sites;

Health Wellness

Relieve Stress Anxiety Tensions

Holiday Stress

Mind Body Yoga

Mesothelioma

Mesothelioma diagnosis: What You Need To Know

Daily Recommended Relaxation

Transcendental Meditation