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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 16, 2008 at 9:21 AM
Subject: Occupational risk factors for endometrial cancer among textile workers in Shanghai, China.
To: mesothelioma77@gmail.com
[1]Am J Ind Med. 2008 Jul 14;
Wernli KJ, Ray RM, Gao DL, Fitzgibbons ED, Camp JE, Astrakianakis G, Seixas N, Li W, De Roos AJ, Feng Z, Thomas DB, Checkoway H
OBJECTIVE: A case-cohort study was conducted to investigate associations between occupational exposures and endometrial cancer nested within a large cohort of textile workers in Shanghai, China. METHODS: The study included 176 incident endometrial cancer cases diagnosed from 1989 to 1998 and a randomly-selected age-stratified reference subcohort (n = 3,061). Study subjects' complete work histories were linked to a job-exposure matrix developed specifically for the textile industry to assess occupational exposures. Hazard ratios (HR) and 95% confidence intervals were calculated using Cox proportional hazards modeling adapted for the case-cohort design, adjusting for age at menarche and a composite variable of gravidity and parity. RESULTS: An increased risk of endometrial cancer was detected among women who had worked for >/=10 years in silk production (HR = 3.8, 95% CI 1.2-11.8) and had exposure to silk dust (HR = 1.7, 95% CI 0.9-3.4). Albeit with few exposed women (two cases and eight subcohort women), there was a 7.4-fold increased risk associated with >/=10 years of silica dust exposure (95% CI 1.4-39.7). CONCLUSIONS: The findings suggest that some textile industry exposures might play a role in endometrial carcinoma and should be further replicated in other occupational settings. Am. J. Ind. Med. (c) 2008 Wiley-Liss, Inc.
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Source: http://www.hubmed.org/display.cgi?uids=18626909
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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Jul 16, 2008 at 9:21 AM
Subject: Occupational risk factors for endometrial cancer among textile workers in Shanghai, China.
To: mesothelioma77@gmail.com
[1]Am J Ind Med. 2008 Jul 14;
Wernli KJ, Ray RM, Gao DL, Fitzgibbons ED, Camp JE, Astrakianakis G, Seixas N, Li W, De Roos AJ, Feng Z, Thomas DB, Checkoway H
OBJECTIVE: A case-cohort study was conducted to investigate associations between occupational exposures and endometrial cancer nested within a large cohort of textile workers in Shanghai, China. METHODS: The study included 176 incident endometrial cancer cases diagnosed from 1989 to 1998 and a randomly-selected age-stratified reference subcohort (n = 3,061). Study subjects' complete work histories were linked to a job-exposure matrix developed specifically for the textile industry to assess occupational exposures. Hazard ratios (HR) and 95% confidence intervals were calculated using Cox proportional hazards modeling adapted for the case-cohort design, adjusting for age at menarche and a composite variable of gravidity and parity. RESULTS: An increased risk of endometrial cancer was detected among women who had worked for >/=10 years in silk production (HR = 3.8, 95% CI 1.2-11.8) and had exposure to silk dust (HR = 1.7, 95% CI 0.9-3.4). Albeit with few exposed women (two cases and eight subcohort women), there was a 7.4-fold increased risk associated with >/=10 years of silica dust exposure (95% CI 1.4-39.7). CONCLUSIONS: The findings suggest that some textile industry exposures might play a role in endometrial carcinoma and should be further replicated in other occupational settings. Am. J. Ind. Med. (c) 2008 Wiley-Liss, Inc.
___
Source: http://www.hubmed.org/display.cgi?uids=18626909
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