Skin Cancer Charts Graphs: Fwd: Effect of childhood cancer treatment on fertility markers in adult male long-term survivors.

Friday, October 3, 2008

---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Sun, Sep 28, 2008 at 4:45 AM
Subject: Effect of childhood cancer treatment on fertility markers in adult male long-term survivors.
To: mesothelioma77@gmail.com

[1]Pediatr Blood Cancer. 2008 Sep 25;
van Casteren NJ, van der Linden GH, Hakvoort-Cammel FG, Hählen K, Dohle GR, van den Heuvel-Eibrink MM

BACKGROUND: Although it is accepted that pediatric cancer treatment harbors a risk of gonadal damage, large cohort studies using up-to-date fertility markers are lacking. PROCEDURE: The aim of our study was to evaluate the gonadal toxicity of childhood cancer treatment using fertility markers. We included 248 adult male long-term survivors of childhood cancer. Median age at diagnosis: 5 years, median age at follow-up: 24 years, median follow-up time 18 years. We evaluated patient characteristics, treatment modalities, testicular size, and endocrinological parameters including Inhibin B, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone. RESULTS: The median value of Inhibin B in the cancer survivor group was 126 ng/L versus 177 ng/L in the control group (P

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Source: http://www.hubmed.org/display.cgi?uids=18819129
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